A study published this week in the journal Pigment Cell & Melanoma Research has discovered that genes have a better influence than previously thought not just on how many moles you have but in addition where they are in your body.
Survival of skin cancer could be influenced by gender, with female patients demonstrating higher rates of survival for this melanoma sites looking after occur in the low body, than men rather, who are generally affected in top of the body, scalp and neck.
In this study, the team from King’s College London analysed a sizable number of 3,200 healthy twins, female predominately, and counted moles on the neck and head, back, chest and abdomen, upper limbs and lower limbs.
They unearthed that:
- In women, the best genetic impact on mole count was on the rear and abdomen (26%), and the greatest on the reduced limbs (69%)
- The larger quantity of moles on women’s lower limbs is unlikely to be because of sun exposure alone but right down to a sex-specific genetic make up
Lead researcher Dr Alessia Visconti, from the Department of Twin Research at King’s College London, said: “We’ve known for a while that moles really are a major risk factor for melanoma skin cancer. With this specific research we now realize that not only the amount but also the place of moles on your body is in large part as a result of genetics.
“Our results enhance previous evidence that indicates greater sun exposure alone is unlikely to function as the reason why women do have more moles on the legs.
“While sun exposure does subscribe to mole count and skin cancer risk, policymakers, campaigners and health researchers should take the sex-specific genetic element under consideration when developing ways of prevent and treat skin cancer.”