Cannabis reduces OCD symptoms by half in the short-term

People with obsessive-compulsive disorder, or OCD, report that the severe nature of these symptoms was reduced by approximately half within four hours of smoking cannabis, based on a Washington State University study.

The researchers analyzed data inputted in to the Strainprint app by those who self-identified as having OCD, an ailment characterized by intrusive, persistent thoughts and repetitive behaviors such as for instance compulsively checking in case a hinged door is locked. After smoking cannabis, users with OCD reported it reduced their compulsions by 60%, intrusions, or unwanted thoughts, by 49% and anxiety by 52%.

The scholarly study, recently published in the Journal of Affective Disorders, also unearthed that higher cannabis and doses with higher concentrations of CBD, or cannabidiol, were related to larger reductions in compulsions.

“The outcome overall indicate that cannabis might have some beneficial short-term although not really long-term effects on obsessive-compulsive disorder,” said Carrie Cuttler, the study’s corresponding author and WSU assistant professor of psychology. “In my experience, the CBD findings are promising since it just isn’t intoxicating really. This is a location of research that will take advantage of clinical trials taking a look at changes in compulsions really, anxiety and intrusions with pure CBD.”

The WSU study drew from data in excess of 1,800 cannabis sessions that 87 individuals logged to the Strainprint app over 31 months. The number of years period allowed the researchers to assess whether users developed tolerance to cannabis, but those effects were mixed. As people continued to make use of cannabis, the associated reductions in intrusions became smaller suggesting these were building tolerance slightly, however the relationship between reductions and cannabis in compulsions and anxiety remained fairly constant.

Traditional treatments for obsessive-compulsive disorder include exposure and response prevention therapy where people’s irrational thoughts around their behaviors are directly challenged, and prescribing antidepressants called serotonin reuptake inhibitors to cut back symptoms. While these treatments have results for many patients, they cannot cure the disorder nor do they work nicely for you with OCD.

“We’re wanting to build knowledge about the connection of cannabis use and OCD because it’s a place that’s really understudied,” said Dakota Mauzay, a doctoral student in Cuttler’s lab and first author on the paper.

Aside from their particular research, the researchers found just one other human study on this issue: a tiny clinical trial with 12 participants that revealed that there have been reductions in OCD symptoms after cannabis use, but we were holding not much bigger than the reductions linked to the placebo.

The WSU experts noted any particular one of the limitations of the study was the shortcoming to utilize a placebo control and an “expectancy effect” may may play a role in the results, meaning when people be prepared to feel from something they often do better. The data was from the self-picked sample of cannabis people also, and there clearly was variability in the outcome meaning that not everyone experienced exactly the same reductions in signs or symptoms after applying cannabis.

On the other hand, Cuttler said this analysis of user-provided details via the Strainprint app was specially valuable because it supplies a good sized data set and the participants were utilizing market cannabis inside their home environment, instead of grown cannabis in a laboratory that might affect their responses federally. Strainprint’s app is supposed to help customers determine which kinds of cannabis work the most effective for them, nevertheless the business provided the WSU scientists free use of users’ anonymized info for research functions.

Cuttler reported this scholarly study highlights that further research, particularly clinical trials on the cannabis constituent CBD, may reveal the therapeutic potential for individuals with OCD.

This could be the fourth study Cuttler and her colleagues have got conducted examining the results of cannabis on various mental health problems using the data supplied by the app produced by the Canadian company Strainprint. Others include reports how cannabis impacts PTSD signs and symptoms, reduces headache soreness, and affects mental well-being.

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Materials given by Washington State University. Original published by Sara Zaske. Take note: Content might be edited for type and length.

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